Simon Hill Living Proof 12-Week Protocol
By applying this skill, a user can design and execute a fully evidence-based, personalized health optimization protocol that tests, intervenes on, and retests the 10 biological and functional markers most predictive of longevity across four key body systems.
// TL;DR
The Simon Hill Living Proof 12-Week Protocol is an evidence-based health optimization framework that tests, intervenes on, and retests the 10 biomarkers most predictive of longevity across four body systems: cardiovascular, metabolic, musculoskeletal, and psychological/emotional well-being. Use it when you want a structured, measurable health plan from scratch — especially if you feel overwhelmed by conflicting health advice but lack a specific, actionable framework. It works by establishing a quantified Longevity Score baseline, applying 12 weeks of progressively stacked lifestyle habits, then retesting to produce measurable proof of change. Designed to deliver meaningful results even at 70–80% adherence.
// When should you use the Living Proof 12-Week Protocol?
Use this skill when a user wants to build a structured, science-backed health and longevity plan from scratch — especially when they feel overwhelmed by information but lack a specific, measurable, actionable framework. Also use it when someone wants to prioritize the highest-leverage health interventions given time and budget constraints.
// What information do you need before starting the protocol?
- User's current health data
Any available blood work (especially ApoB, triglycerides, fasting glucose, HbA1c), functional test results (grip strength, VO2 Max or shuttle test score), blood pressure readings, and DEXA scan results if available. - User's cardiovascular risk profilerequired
History of smoking, hypertension, cardiovascular events, Type 2 diabetes, or known elevated Lp(a). Used to calibrate ApoB targets and longevity score. - User's sex, age, and menopausal status (if applicable)required
Many of the 10 Truths have sex- and age-adjusted optimal ranges. Postmenopausal women require specific attention to bone mineral density targets. - User's current lifestyle baseline
Approximate weekly exercise volume, dietary patterns, sleep quality, and a self-assessed flourishing score. - User's goal focus
Which of the four Key Systems the user most wants to move the needle on: cardiovascular, metabolic, musculoskeletal, or psychological/emotional well-being.
// What core principles drive the Living Proof Protocol?
What Gets Measured Can Be Optimized
The protocol insists on baseline testing before any intervention begins. Without a measured starting point, you are 'throwing darts at a dartboard with the lights on.' Measurement turns the lights on.
The Three Criteria for a Truth
Every metric included in the 10 Truths must satisfy three criteria simultaneously: (1) it is a great predictor of longevity, (2) it can be relatively easily measured, and (3) it can be shifted in a favorable direction with a specific, evidence-based lifestyle protocol.
Test — Intervene — Retest
The entire protocol is structured as a three-phase loop: establish a quantified baseline (the Longevity Score), apply the 12-week challenge interventions, then retest all 10 Truths to produce measurable proof of change.
Four Key Systems
All 10 Truths map to one of four Key Systems of the body: cardiovascular, metabolic, musculoskeletal, and psychological/emotional well-being. Any health plan that ignores one of these four systems is incomplete.
Personal Fat Threshold
Each person has a genetically determined capacity to store fat safely in subcutaneous adipose tissue. Once that threshold is exceeded, fat spills into the liver, pancreas, and circulation, driving metabolic disease. The metabolic Truths (triglycerides, waist-to-height ratio, fasting glucose, HbA1c) serve as the window into whether someone has exceeded their personal fat threshold.
Progressive Habit Stacking
The 12-week challenge starts gently in week one and builds in difficulty and complexity each week. Each week has a distinct theme (e.g., protein in week one). The goal is that by week 12, the full evidence-based protocol is in practice simultaneously.
Imperfect Adherence Is Acceptable
The protocol is designed so that 70–80% adherence still produces meaningful improvements in the Longevity Score. Demanding perfect adherence is counterproductive and has been factored out of the design.
Bones as a Savings Account
Bone mineral density should be built early in life — in one's 20s, 30s, and 40s — because the reserves built early determine fracture risk in later decades. The musculoskeletal interventions apply at any age, but the earlier the investment, the greater the return.
Loneliness Kills
Drawing on the Harvard Study of Adult Development (80 years of follow-up), the quality of social relationships is a stronger predictor of happiness and longevity than LDL cholesterol, smoking, or income above ~$75,000. Emotional well-being is not a soft add-on; it is a hard longevity variable.
Service Attenuates Stress
People who are highly stressed but consistently of service to others do not show increased mortality risk, unlike highly stressed people who are not of service. Being of service appears to buffer the physiological damage of stress, likely via inflammation pathways.
// How do you apply the Living Proof Protocol step by step?
- 1
Identify the user's cardiovascular risk profile
Ask: Do they have a history of smoking, hypertension, cardiovascular events, Type 2 diabetes, or elevated Lp(a)? Classify them as HIGH RISK or LOW RISK. This determines their ApoB target: under 50 mg/dL (high risk) or under 80 mg/dL (low risk). Also recommend a once-off Lp(a) test if never done — Lp(a) is ~100% genetically driven, cannot be modified by lifestyle, and if elevated, requires more aggressive ApoB reduction.
- 2
Measure the 10 Truths to establish the Longevity Score baseline
Walk through each Truth by system. CARDIOVASCULAR: (1) ApoB — blood test (request from physician or use a service like Inside Tracker); (2) Blood pressure — home automatic cuff (e.g., Omron), rest 5 minutes, legs uncrossed, cuff at heart level, target 120/80 mmHg; (3) VO2 Max — either lab treadmill/bike test OR the 20-metre beep/shuttle test (two cones 20m apart, free pacing app, record level and shuttle number at failure, correlates at r=0.92 with VO2 Max). METABOLIC: (4) Triglycerides — blood test; (5) Waist-to-height ratio — tape measure, waist circumference divided by height; (6) Fasting blood glucose — blood test; (7) HbA1c — blood test (3-month average glucose). MUSCULOSKELETAL: (8) Grip strength — $20–$30 dynamometer, test left and right hands three times each, take average, adjust for age and sex; (9) Bone mineral density — DEXA scan (e.g., DexaFit), produces a T-score relative to average 30-year-old; note: osteopenia = T-score −1.0 to −2.5, osteoporosis = below −2.5. PSYCHOLOGICAL: (10) Flourishing Scale — 8-question validated tool (score 1–7 per question, max 56), assessing purposeful life, supportive relationships, daily engagement, contribution to others' well-being, competence, self-regard, optimism, and social respect.
- 3
Calculate the Longevity Score
Each Truth is scored as suboptimal (0 points), normal (0.5 points), or optimal (1 point). Age, sex, and cardiovascular risk profile adjust what 'optimal' means for specific Truths. The total across all 10 Truths produces the Longevity Score. This is the pre-intervention baseline. Encourage the user to record this — seeing it move is a primary motivation driver.
- 4
Map the user's weakest Truths to the Four Key Systems and prioritize intervention focus
A user scoring suboptimal on ApoB, blood pressure, and VO2 Max has a cardiovascular priority. A user with elevated triglycerides, fasting glucose, and increased waist-to-height ratio has a metabolic priority. A user with low grip strength or a T-score indicating osteopenia/osteoporosis has a musculoskeletal priority. A flourishing score below 40 signals psychological/emotional well-being needs attention. Name the priority system explicitly so the user understands where the 12-week challenge will move the needle most.
- 5
Introduce the 12-week progressive habit challenge across all four domains
The challenge is organized into 12 weekly themes, building progressively. The four intervention domains are: NUTRITION: optimize total protein intake (distribute across meals, emphasize plant protein sources); shift cooking fats to olive oil or avocado oil away from butter, tallow, coconut, or palm oil. EXERCISE: build toward 150 minutes per week of Zone 2/3 cardio training; add resistance training to address grip strength and bone mineral density (weight-bearing movements with ground reaction force — jogging, skipping — stimulate bone; heavy compound lifts stimulate muscle). SLEEP: addressed in weekly themes with evidence-based sleep hygiene practices. EMOTIONAL WELL-BEING: structured exercises around service to others, relationship quality, and purposeful engagement. Start week one gently (theme: protein); each subsequent week adds one new focus while maintaining prior habits. Do not attempt to introduce all habits simultaneously — progressive stacking is the mechanism.
- 6
Apply the cardiovascular intervention protocol to ApoB specifically
ApoB is the sum total of all atherogenic lipoproteins (LDL, IDL, VLDL — each carries exactly one ApoB molecule; HDL does not). ApoB is a superior predictor of atherosclerotic cardiovascular disease compared to LDL cholesterol in 20–30% of cases. If the user has never tested ApoB, treat this as the highest-priority blood test to obtain. The primary lifestyle lever for ApoB reduction is dietary fat composition — this intersects with the nutrition habits in the weekly challenge.
- 7
Apply the metabolic intervention protocol based on personal fat threshold signals
If two or more of the four metabolic Truths are suboptimal (elevated triglycerides, elevated waist-to-height ratio, elevated fasting glucose, elevated HbA1c), the user has likely exceeded their personal fat threshold. The primary intervention is energy balance (reducing energy toxicity) combined with exercise to stimulate mitochondrial health. Weight loss of 10–15 kg typically normalizes these markers in overweight/obese individuals; even 7–8 kg in individuals with normal BMI can normalize them. Do not rely solely on BMI — 1 in 6 people with Type 2 diabetes have normal BMI.
- 8
Apply the musculoskeletal intervention protocol for grip strength and bone mineral density
For grip strength: resistance training is the primary lever. From age 40, expect 2–3% annual strength loss in sedentary populations — this is not inevitable with resistance training. The goal is not grip-specific wrist curls but compound strength that grip strength proxies. For bone mineral density: weight-bearing exercise with ground reaction force greater than daily walking (jogging, skipping, hopping) stimulates osteoblast activity. Hormones mediate this — estrogen is the key signal in women; postmenopausal women should discuss pharmacotherapy (e.g., estrogen therapy where not contraindicated) with a physician. If T-score indicates osteoporosis, refer to a supervised bone health clinic before prescribing jumping or jogging. Bone responds even at age 80–90 — it is never too late, but safety must be matched to baseline risk.
- 9
Apply the psychological/emotional well-being intervention protocol
Target areas identified by low flourishing scale scores: (a) relationship quality — invest in depth and frequency of meaningful social contact; (b) service to others — structured volunteering, mentoring, or consistent acts of contribution; (c) purpose — identify activities that produce engagement and meaning. The research signal is clear: highly stressed individuals who are consistently of service to others do not show elevated mortality risk. This is a modifiable buffer. Spending more than 75% of time alone is associated with significantly elevated loneliness risk — Solitude itself is not harmful, but chronic isolation is.
- 10
Retest all 10 Truths at the conclusion of the 12-week challenge
Repeat every test from Step 2 using the same protocols and conditions to ensure comparability. Recalculate the Longevity Score. The delta between baseline and post-challenge score is the primary output — it is the measurable proof that the protocol worked. If a specific Truth has not moved, interrogate adherence in the intervention most directly linked to that Truth before concluding the intervention is ineffective.
// What does the protocol look like for real people?
A 45-year-old male office worker with no known cardiovascular history, slightly overweight, who exercises casually but has never had comprehensive blood work done.
Classify as LOW RISK (no smoking, hypertension, CVD events, T2D, or known Lp(a) elevation) — ApoB target under 80 mg/dL. Run full 10 Truths baseline: blood panel for ApoB, triglycerides, fasting glucose, HbA1c; home blood pressure cuff measurement; shuttle/beep test for VO2 Max; dynamometer for grip strength; DEXA scan to establish T-score and visceral fat baseline; flourishing scale self-assessment. Calculate Longevity Score. If metabolic Truths are suboptimal (likely given overweight status), prioritize energy balance, protein optimization (target gram/kg body weight, emphasize plant protein), and Zone 2 cardio build to 150 min/week. Retest at 12 weeks.
A 58-year-old postmenopausal woman, normal BMI, active runner, who has never had a DEXA scan and has a family history of cardiovascular disease.
Classify as potentially HIGH RISK pending Lp(a) test — order Lp(a) immediately; if elevated, ApoB target drops to under 50 mg/dL. Treat bone mineral density as the highest-priority unknown — DEXA scan is urgent given postmenopausal status and no prior scan; T-score result determines whether exercise prescription includes supervised bone-loading or standard weight-bearing protocol. Running is already providing VO2 Max benefit — evaluate shuttle test or lab VO2 Max to confirm above-average cardiorespiratory fitness. Flourishing scale may be strong given active lifestyle — check relationship quality and service questions specifically. Resistance training is likely the key gap: add compound lifting to address grip strength and bone stimulus alongside running.
A 35-year-old who is lean and highly fit but reports chronic stress, social isolation since a major life transition, and low sense of purpose.
Cardiovascular and musculoskeletal Truths likely score well — VO2 Max probably above average, grip strength likely adequate, ApoB and metabolic markers likely normal. The Longevity Score gap will appear almost entirely on the flourishing scale. Interventions: structured service activity (volunteering, coaching, mentoring) to activate the stress-buffering effect of contribution; deliberate relationship investment (schedule regular deep social contact, reduce time alone below 75% of waking hours); purpose-mapping exercise to identify activities that produce genuine engagement. Monitor flourishing scale at retest — quantified improvement in psychological well-being is the primary success metric for this user.
// What mistakes should you avoid with this protocol?
- Testing ApoB without accounting for cardiovascular risk profile — the optimal ApoB target is not universal; it is under 50 mg/dL for high-risk individuals and under 80 mg/dL for low-risk individuals. Applying the wrong target produces a false sense of safety.
- Relying on LDL cholesterol instead of ApoB — LDL misclassifies risk in 20–30% of cases because it does not capture IDL and VLDL; always request ApoB specifically.
- Ignoring Lp(a) — approximately 1 in 6 people carry a gene mutation that significantly elevates cardiovascular risk through a mechanism that no lifestyle intervention can modify. Not testing for it means not knowing your true baseline risk.
- Using BMI as a proxy for metabolic health — 1 in 6 people with Type 2 diabetes have normal BMI. The four metabolic Truths (triglycerides, waist-to-height ratio, fasting glucose, HbA1c) are far more informative than BMI.
- Measuring blood pressure incorrectly — must rest 5 minutes beforehand, legs uncrossed, cuff at heart level. Office measurements are less predictive of cardiovascular disease than correctly taken home measurements. White coat effect inflates in-office readings.
- Assuming VO2 Max is fixed by genetics — it is malleable through training. Moving from 'low' to 'average' cardiorespiratory fitness halves risk of death and cardiovascular disease and can be achieved with 150 minutes per week of moderate-intensity exercise.
- Skipping the DEXA scan, especially for postmenopausal women — three postmenopausal women in a retreat cohort discovered they had osteoporosis for the first time through this protocol. Unknown osteoporosis changes exercise prescriptions, dietary priorities, and pharmacotherapy decisions.
- Treating bone health as relevant only after age 50 — bones are a savings account. The musculoskeletal interventions should begin in one's 20s and 30s to build reserves that protect against fracture risk in later decades.
- Dismissing psychological/emotional well-being as a 'soft' metric — the Harvard Study of Adult Development (80 years of follow-up) found relationship quality outperforms LDL cholesterol and smoking as a predictor of longevity. This Truth is not optional.
- Demanding 100% adherence and abandoning the protocol when it slips — the protocol is designed to produce meaningful health improvements at 70–80% adherence. Perfectionism is a protocol killer.
- Introducing all 12 habits simultaneously in week one — the progressive weekly stacking structure exists for a reason. Overloading week one leads to collapse. Start gently, build each week.
// What key terms should you know for the Living Proof Protocol?
- The 10 Truths
- The ten specific, measurable biomarkers and functional tests selected because they simultaneously satisfy three criteria: they are great predictors of longevity, they are relatively easily measured, and they can be shifted in a favorable direction by specific evidence-based lifestyle protocols.
- Longevity Score
- The composite score produced by rating each of the 10 Truths as suboptimal (0 points), normal (0.5 points), or optimal (1 point), adjusted for age, sex, and cardiovascular risk profile. The score at baseline versus post-challenge provides quantified proof of health improvement.
- Four Key Systems
- The four biological and psychological systems that the 10 Truths collectively assess: cardiovascular, metabolic, musculoskeletal, and psychological/emotional well-being.
- ApoB
- Apolipoprotein B — a protein present on every atherogenic lipoprotein (LDL, IDL, VLDL) but absent from HDL. Measuring ApoB gives the total burden of all atherogenic lipoproteins in circulation, making it a superior predictor of atherosclerotic cardiovascular disease compared to LDL cholesterol alone.
- Lp(a) (LP little a)
- Lipoprotein(a) — a subclass of LDL that is particularly atherogenic and approximately 100% genetically determined. It cannot be meaningfully modified by lifestyle. Elevated Lp(a) (above 30 mg/dL) places the individual at 1–1.5 times lifetime cardiovascular event risk and requires a more aggressive ApoB reduction target (under 50 mg/dL).
- Personal Fat Threshold
- Each individual's genetically determined maximum capacity to store fat safely in subcutaneous adipose tissue. Once this threshold is exceeded, fat spills into the liver, pancreas, and circulation as ectopic fat, driving insulin resistance, elevated triglycerides, elevated fasting glucose, elevated HbA1c, and eventually Type 2 diabetes and non-alcoholic fatty liver disease.
- Atherogenic Lipoproteins
- Lipoproteins capable of penetrating the artery wall and depositing cholesterol to form plaque. Includes LDL, IDL, and VLDL — all carry one ApoB molecule each. HDL is not atherogenic.
- Atherosclerotic Cardiovascular Disease
- The most common form of cardiovascular disease, characterized by plaque buildup inside arteries driven by lifetime accumulation of atherogenic lipoproteins. Can lead to heart attack (coronary obstruction) or stroke (cerebral obstruction).
- T-Score
- The output of a DEXA scan, measuring an individual's bone mineral density relative to the average healthy 30-year-old adult. A T-score of 0 equals that average; −1.0 to −2.5 indicates osteopenia; below −2.5 indicates osteoporosis. Each standard deviation drop (approximately 10% reduction) doubles fracture risk.
- Beep Test / Shuttle Test
- A validated field test for estimating VO2 Max. The user runs between two cones set 20 metres apart, paced by progressively accelerating audio beeps. The level and shuttle number at which the user fails (missing two consecutive beeps) is converted to an estimated VO2 Max using a reference table. Correlation with directly measured VO2 Max is r=0.92.
- Flourishing Scale
- An 8-question, clinically validated psychometric tool developed to assess psychological well-being across dimensions of purpose, relationships, engagement, contribution to others, competence, self-regard, optimism, and social respect. Each question scored 1–7; maximum score 56. Used as the 10th Truth to provide a quantified baseline for psychological/emotional well-being.
- Test — Intervene — Retest
- The core structural principle of the Living Proof Challenge: measure all 10 Truths to generate a Longevity Score baseline, apply 12 weeks of evidence-based lifestyle interventions, then retest all 10 Truths to produce measurable proof of health change.
- Energy Toxicity
- Roy Taylor's term for the chronic energy surplus state that drives fat accumulation beyond the personal fat threshold into the liver and pancreas, progressively impairing insulin sensitivity and beta cell function, and ultimately leading to non-alcoholic fatty liver disease and Type 2 diabetes.
- Zone 2/3 Training
- Aerobic exercise performed at moderate to moderately-high intensity, the primary modality used in the 12-week challenge to improve VO2 Max and cardiorespiratory fitness. The challenge targets building to 150 minutes per week of this training by week 12.
- Waist-to-Height Ratio
- Waist circumference divided by height — used as a superior alternative to BMI for assessing fat distribution and visceral adiposity. Increased waist-to-height ratio signals that fat is being stored abdominally (viscerally), indicating the personal fat threshold may have been exceeded.
// FREQUENTLY ASKED QUESTIONS
What is the Simon Hill Living Proof 12-Week Protocol?
The Simon Hill Living Proof 12-Week Protocol is an evidence-based health optimization framework that measures 10 biomarkers most predictive of longevity, applies 12 weeks of progressive lifestyle interventions, then retests to prove change. The 10 Truths span four systems: cardiovascular, metabolic, musculoskeletal, and psychological/emotional well-being. Together they produce a single Longevity Score you can track before and after.
What are the 10 Truths in the Living Proof Protocol?
The 10 Truths are ApoB, blood pressure, and VO2 Max (cardiovascular); triglycerides, waist-to-height ratio, fasting glucose, and HbA1c (metabolic); grip strength and bone mineral density (musculoskeletal); and the Flourishing Scale (psychological). Each was selected because it predicts longevity well, is easily measured, and can be shifted with a specific evidence-based lifestyle protocol.
How do I calculate my Longevity Score?
Score each of the 10 Truths as suboptimal (0 points), normal (0.5 points), or optimal (1 point), then sum them for a total out of 10. What counts as 'optimal' is adjusted for your age, sex, and cardiovascular risk profile. Record your baseline score before starting the challenge — seeing it move after 12 weeks is a primary motivation driver.
How do I start the 12-week challenge without getting overwhelmed?
Start week one gently with a single theme (protein) and add one new focus each week while maintaining prior habits — this is called progressive habit stacking. Never introduce all habits simultaneously; overloading week one leads to collapse. By week 12, the full evidence-based protocol across nutrition, exercise, sleep, and emotional well-being is running at once.
How does this protocol compare to generic health advice or fitness plans?
Unlike generic advice, this protocol requires baseline measurement before any intervention — without a measured starting point, you're 'throwing darts with the lights off.' It also uses ApoB instead of LDL (which misclassifies risk in 20–30% of cases), rejects BMI as a metabolic proxy, and treats psychological well-being as a hard longevity variable, not a soft add-on.
When should I use the Living Proof Protocol?
Use it when you want a structured, science-backed longevity plan from scratch, especially if you feel overwhelmed by conflicting information but lack a specific, measurable framework. It's also ideal when you need to prioritize the highest-leverage interventions given limited time and budget, since mapping your weakest Truths tells you exactly which system to focus on first.
What results can I expect after 12 weeks?
You can expect a measurable improvement in your Longevity Score, driven by favorable shifts in your weakest Truths. Even at 70–80% adherence the protocol is designed to produce meaningful change. Moving from low to average cardiorespiratory fitness halves risk of death; 10–15 kg weight loss can normalize metabolic markers. The delta between baseline and retest is your proof.
Why does the protocol use ApoB instead of LDL cholesterol?
ApoB counts every atherogenic lipoprotein (LDL, IDL, VLDL each carry exactly one ApoB molecule), while LDL cholesterol misses IDL and VLDL and misclassifies risk in 20–30% of cases. Your target depends on risk: under 50 mg/dL if high-risk, under 80 mg/dL if low-risk. If you've never tested ApoB, it's the highest-priority blood test to obtain.
Do I need expensive lab tests to do this protocol?
No — several Truths use inexpensive at-home tools: a home blood pressure cuff, a $20–$30 dynamometer for grip strength, a tape measure for waist-to-height ratio, a free beep-test app for VO2 Max, and a self-scored Flourishing Scale. A blood panel (ApoB, triglycerides, glucose, HbA1c) and a DEXA scan for bone density do require lab access.
What is Lp(a) and why should I test it once?
Lp(a) is a particularly atherogenic subclass of LDL that is roughly 100% genetically determined and cannot be modified by lifestyle. About 1 in 6 people carry a mutation that significantly elevates cardiovascular risk. Because it's fixed, you only need to test it once — but if elevated (above 30 mg/dL), it drops your ApoB target to under 50 mg/dL.
Does the protocol require perfect adherence?
No — the protocol is intentionally designed so that 70–80% adherence still produces meaningful improvements in your Longevity Score. Demanding 100% adherence is counterproductive and has been factored out of the design. Perfectionism is a protocol killer; when a habit slips, resume rather than abandon.